Wellness > Managing Mesothelioma Pain

Cancer causes pain by extension of the tumor into soft tissues, nerve compression, getting into the bones, and by raising intercranial pressure.

The World Health Organization lists drugs used to fight cancer pain:

Category Basic drugs Alternatives
Non-opioids aspirin
paracentamol
ibuprofen
indometacin
choline magnesium trisalyicylate
diflunisal
naproxen
diclofenac
Opioids for mild to moderate pain codeine dihydrocodeine
dextropropoxyphene
standardized opium
tramadol
Opioids for moderate to severe pain morphine methadone
hydromorphone
oxycodone
levorphanol
pethidine
buprenorphine
Opioid antagonist naloxone  
Antidepressants amitriptyline imipramine
Anticonvulsants carbamazepine valproic acid
Corticosteroids prednisolone
dexamethasone
prednisone
betamethasone

 

According to the WIO, some pains respond well to a combination of drugs, such as an opioid and a non-opioid or a coritcosteroid with an opioid.

Doctors also consider whether the pain is neuropathic, in which case antidepressants and anticonvulsants may be better options.

Analgesics are usually given by mouth, although rectal suppositories may be used for patients with vomiting or gastrointestinal obstruction.

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